Alfredo Santillan-Gomez, MD, MPH, FACS

Dr. Alfredo A. Santillan-Gomez is a board certified General Surgeon with a specialty in Surgical Oncology. He is fully devoted to the oncology and endocrine surgical fields.

Dr. Santillan graduated with honors from the Institute of Technology, Monterrey, N.L., Mexico and did a Masters Degree in Public Health at Harvard University. He completed General Surgery training at Texas Tech University. As a senior surgery resident he was awarded with the Allando Ballantyne Fellowship in Head and Neck Surgery at M.D. Anderson Cancer Center, University of Texas.

He then went on for advanced training in Surgical Oncology at Moffitt Cancer and Research Center, University of South Florida, in Tampa. Prior to joining Texas Oncology, Dr. Alfredo Santillan-Gomez served for seven years as an Associate Professor in the division of Surgical Oncology and Endocrine Surgery at The University of Texas Health at San Antonio and is currently an adjunct Professor of the Division of Epidemiology and Biostatistics at The University of Texas Health Science Center at San Antonio.

Dr. Santillan’s areas of expertise include oncologic and endocrine surgery with emphasis on surgical diseases of the breast, thyroid, parathyroid, adrenal, colon, melanoma, pancreas and sarcoma. He has practiced in San Antonio since 2009 and is recognized as a leader in cancer and endocrine surgery with extensive surgical experience. 

He is a Hidden Scar trained surgeon on advanced minimally invasive and minimal access surgical approaches that deliver optimal clinical and aesthetic outcomes for patients with breast cancer.

He is a co-author of numerous publications and research projects with special interest in cancer biology and epidemiology and is a member of the Society of Surgical Oncology, the American Association of Endocrine Surgeons, the American College of Surgeons, the American Society of Breast Surgeons.

He is one of the few high thyroid volume surgeons in South Texas, according to the American Thyroid Association guidelines, with more than 100 thyroid surgeries per year.


  • Fellowship in Surgical Oncology
    Moffitt Cancer Center, University of South Florida, Tampa, FL

  • Fellowship in Head and Neck Oncology
    Allando Ballantyne Fellowship in Head and Neck Surgery at M.D. Anderson Cancer Center, University of Texas, Houston, TX

  • Residency in General Surgery
    Texas Tech University Health Sciences Center, El Paso, TX

  • Master of Public Health, Quantitative Methods
    Harvard T.H. Chan School of Public Health, Boston, MA

  • Medical Doctorate
    Monterrey Institute of Technology and Higher Education, Monterrey, N.L., México


  • American Association of Endocrine Surgeons

  • American College of Surgeons

  • American Head and Neck Society

  • American Society of Breast Surgeons

  • American Society of Clinical Oncology

  • Society of Surgical Oncology

Conditions & Procedures

  • Endocrine : Thyroid, Parathyroid, Adrenal
    - Thyroidectomy, Central neck lymph node dissection, Lateral neck lymph node dissection, Recurrent laryngeal nerve monitoring, Minimal invasive parathyroidectomy, Robotic and laparoscopic adrenalectomy.
    - High volume category of thyroid procedures.

  • Melanoma & Soft Tissue Sarcoma

    Excision of skin melanoma, skin graft after excision, Sentinel lymph node biopsy, Lymphadenectomy, Isolated limb infusion, Resection of sarcoma.

  • Complex Gastrointestinal Surgical Oncology & Pancreas

    Gastric cancer
    Total-Subtotal-Partial Gastrectomy

    Small bowel & Colon Cancer
    Laparoscopic right hemicolectomy, Laparoscopic subtotal colectomy, Robotic sigmoidectomy

    Rectal Cancer
    Robotic Low Anterior Resection, Robotic Abdominoperineal Resection, Robotic coloanal anastomosis

    Distal pancreatectomy, Whipple procedure, Pancreatic enucleation


    Peritoneal Cancer & Appendiceal Cancer 
    Cytoreductive surgery
    HIPEC intraperitoneal chemotherapy